New genetic markers for male fertility

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New genetic markers for male infertility.

PURPOSE OF REVIEW The purpose of this review is to highlight the most important advances in the field of genetics of male infertility, with particular attention to primary articles dealing with the identification of new genetic and epigenetic markers that could be translated into clinical practice in the near future. RECENT FINDINGS Copy number variations (CNVs) of the Y chromosome (gr/gr) de...

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We are in the age of genetic discovery. Now the human genome has been completely sequenced1, there will be increasing understanding and ability to manipulate biochemical pathways downstream of genes. At the same time, further development of in vitro fertilization (IVF) and intracytoplasmic sperm injection(ICSI) will enable procreation in situations that were formerly impossible and when there m...

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Molecular Markers for Fertility in Farm Animals

A genetic marker is a gene or DNA sequence with known localization on a chromosome. It can be de-scribed as a variation that can be measured or detected by a suitable method, and can be used subsequently to detect the presence of a specific genotype. Such variations occurring at chromosomal or DNA level can serve as genetic markers. The progress in development of molecular markers suggests thei...

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Symposium: Genetic aspects of male (in)fertility

The Y chromosomal azoospermia factor (AZF) is essential for human spermatogenesis. It has been mapped by molecular deletion analyses to three subintervals in Yq11, AZFa, AZFb, and AZFc, containing a number of genes of which at least some control, post-transcriptionally, the RNA metabolism of other spermatogenesis genes, functionally expressed at different phases of the spermatogenic cycle. Intr...

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molecular markers for fertility in farm animals

a genetic marker is a gene or dna sequence with known localization on a chromosome. it can be de-scribed as a variation that can be measured or detected by a suitable method, and can be used subsequently to detect the presence of a specific genotype. such variations occurring at chromosomal or dna level can serve as genetic markers. the progress in development of molecular markers suggests thei...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2012

ISSN: 1008-682X,1745-7262

DOI: 10.1038/aja.2012.84